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  1. Creig Hoyt, Editor

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    MITOCHONDRIAL DNA CONTENT IN PATIENTS WITH NAION

    The pathophysiology of non-arteritic ischaemic optic neuropathy (NAION) is only incompletely understood. Abu-Amero and Bosley investigated 19 patients with NAION and, compared to a control group of 32, they found increased relative mitochondria DNA content in leucocytes in patients with NAION. They suggest that this may possibly be a response to oxidative stress. A relative increase in mitochondrial DNA content in leucocytes may be a relative risk factor in the development of NAION. See p 823

    COMPLIANCE MONITOR FOR EYE DROPS

    It is well established that patient compliance in self administration of medication is often poor. This may be the result of the inability to recall if an appropriate dose has been administered or what the appropriate dose should …

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