rss
Br J Ophthalmol 2006;90:1209-1210 doi:10.1136/bjo.2006.095307
  • Letter

Haemorrhagic vitreoretinal complications associated with combined antiplatelet agents

  1. E N Herbert1,
  2. B Mokete1,
  3. T H Williamson1,
  4. D A H Laidlaw2
  1. 1Vitreo-Retinal Unit, St Thomas’s Hospital, Lambeth Palace Road, London SE1 7EH, UK
  2. 2Eye, Ear and Mouth Unit, Maidstone General Hospital, Hermitage Lane, Barming, Maidstone ME16 9QQ, UK
  1. Correspondence to: Dr E N Herbert Vitreo-Retinal Unit, St Thomas’s Hospital, Lambeth Palace Road, London SE1 7EH, UK; enherbert{at}doctors.org.uk
  • Accepted 10 May 2006

Antiplatelet agents are increasingly encountered in combination1–3 or taken with non-steroidal anti-inflammatory drugs (NSAIDs), which potentiate their action. We present four cases of intraocular haemorrhage associated with these combinations.

Case 1

An 83 year old man presented with visual acuity reduced to hand motions in both eyes as a result of dense vitreous haemorrhage. He had hypertension, which was being treated, but was not diabetic. Medications included 75 mg clopidogrel once daily and diclofenac.

He underwent a right vitrectomy with cryotherapy and gas tamponade. There was copious intraocular and extraocular bleeding that was difficult to control, significantly prolonging surgery. Postoperatively the acuity was still hand motions with persistent vitreous haemorrhage. Clopidogrel and diclofenac were discontinued before left eye surgery. …

This Article

Services

  1. Request permissions

Responses

  1. Submit a response
  2. No responses published

Social bookmarking

Register for free content


Free sample
This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of BJO.
View free sample issue >>

Free archive
The full back archive is now available for BJO. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006, back to volume 1 issue 1.
Register to access the free archive >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.