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Br J Ophthalmol 2007;91:121-122 doi:10.1136/bjo.2006.100552
  • Letter

Cytological vitreous findings in a patient with infantile neurological cutaneous and articular (CINCA) syndrome

  1. A Adán1,
  2. M Solé2,
  3. B Corcostegui3,
  4. R Navarro4,
  5. A Burés5
  1. 1Instituto de Microcirugía Ocular Barcelona, Barcelona, Spain
  2. 2Department of Pathology, Hospital Clinic de Barcelona, Universidad de Barcelona, Barcelona, Spain
  3. 3Instituto de Microcirugía Ocular Barcelona, Barcelona, Spain
  4. 4Department of Ophthalmology, Hospital Clinic de Barcelona, Universidad de Barcelona, Barcelona, Spain
  5. 5Department of Ophthalmology, Hospital Clinic de Barcelona, Universidad de Barcelona, Barcelona, Spain
  1. Correspondence to: A Adán Department of Ophthalmology, Hospital Clinic de Barcelona, Calle Villarroel 170, Barcelona 08036, Spain;amadan{at}clinic.ub.es
  • Accepted 8 June 2006

The chronic infantile neurological cutaneous and articular (CINCA) syndrome is a rare inflammatory paediatric disease identified by Prieur et al1 in 1987. Ocular manifestations have been observed in 26% of patients2 and include anterior uveitis, abnormal optic disc appearance and posterior inflammation with vitritis and vasculitis.3 This article describes cytological vitreous findings, obtained by pars plana vitrectomy, in patients with CINCA syndrome.

Case report

A 1-month-old boy was initially examined because of a bilateral anterior uveitis for 10 days. He was born after a normal pregnancy. On the second day, however, a generalised urticaria was observed and his serum C reactive protein level was raised. He presented with recurrent fever, leucocytosis, neutrophilia, increased erythrocyte sedimentation rate and raised serum level of immunoglobin (Ig)G. No evidence of …

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