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Br J Ophthalmol 2007;91:1562-1563 doi:10.1136/bjo.2007.115634
  • Letter

Cicatrising conjunctivitis due to paraneoplastic pemphigoid

  1. Tina Rutar1,
  2. Matilda F Chan2,
  3. Nisha R Acharya2,
  4. Ayman Naseri3
  1. 1
    Department of Ophthalmology, University of California San Francisco, San Francisco, CA, USA
  2. 2
    F.I. Proctor Foundation, Department of Ophthalmology, University of California San Francisco, San Francisco, CA, USA
  3. 3
    Department of Ophthalmology, San Francisco VA Medical Center, San Francisco, CA, USA
  1. Dr Tina Rutar, Department of Ophthalmology, University of California San Francisco, 10 Koret Way, K301, San Francisco, CA 94143-0730, USA; tinarutar{at}yahoo.com
  • Accepted 27 January 2007

Ocular cicatricial pemphigoid (OCP) is a putative autoimmune, chronic, inflammatory, subepithelial blistering disease affecting mucous membranes.1 It is characterised by linear deposition of immunoglobulins and complement along epithelial basement membranes.1 In this report, we describe a cicatrising conjunctivitis that was clinically and pathologically similar to ocular cicatricial pemphigoid but occurred concurrently with systemic malignancy.

Case report

A 69-year-old cachectic man with chronic obstructive pulmonary disease presented with painful mouth and skin blisters. He developed a painful red eye 1 week later. Visual acuity was 20/25 on the right and 20/30 on the left. Slit-lamp examination showed bulbar conjunctival injection and an intense papillary reaction of the palpebral conjunctiva on …

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