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The treatment of choice for pterygium is surgical excision. Recurrence is the most common undesirable treatment outcome. Surgery and other modalities of treatment including β-irradiation, topical thiotepa, intraoperative and postoperative use of mitomycin C, 5-fluorouracil (5-FU) and daunorubicin, have been described to reduce recurrence.1–9 Multiple surgery is itself a risk factor for recurrence.9 We present a case in which the fourth surgery for recurrent pterygium resulted in further recurrence, which was thwarted by multiple intralesional injections of 5-FU.
A 34-year-old Afro-Caribbean woman was referred to us in October 2004 for the management of recurrent pterygium in the right eye. She had two previous surgeries, the first in 2002 with conjunctival autograft …