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Br J Ophthalmol 2007;91:399-400 doi:10.1136/bjo.2006.102384
  • Letter

Sympathetic ophthalmia after ruthenium plaque brachytherapy

  1. Nadeem Ahmad1,
  2. Terrence K Soong2,
  3. Sachin Salvi2,
  4. Paul A Rudle2,
  5. Ian G Rennie2
  1. 1Ophthalmology Department, Royal Hallamshire Hospital, Sheffield, UK
  2. 2Royal Hallamshire Hospital, Sheffield, UK
  1. Correspondence to: MrN Ahmad Ophthalmology Department, A Floor, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK; ophthdoc{at}tesco.net
  • Accepted 7 July 2006

Sympathetic ophthalmia is a rare, bilateral inflammatory process with an incidence of 0.03/100 000 in the UK and Ireland.1 It usually follows either penetrating eye injury or intraocular surgery. Although sympathetic ophthalmia has previously been described after irradiation of ocular melanoma,2,3 it has never been reported after simple 106Ru plaque brachytherapy. We present a case which confirms that there is a risk of developing sympathetic ophthalmia after charged-particle therapy in the absence of a penetrating injury of the uveal tract.

Case report

A 41-year-old lady was referred by her optician for a slow-growing iris lesion. Fine needle aspiration biopsy confirmed the diagnosis of ciliary body malignant melanoma. Systemic investigations for metastatic disease were negative. The patient underwent routine surgery for the …

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