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- Published on: 22 March 2016
- Published on: 22 March 2016
- Published on: 22 March 2016Use of Avastin in rat models: Comments.Show More
Dear Editor
We have read Manzano et al’s insightful paper[1] with interest and appreciated the comments concerning the inhibitory effects of bevacizumab on corneal neovascularisation (NV). However, the manuscript had some important aspects that need to be clarified. Cumulative data from numerous basic and clinical studies strongly implicates the central role of VEGF in ocular and corneal angiogenesis. Binding all free-ci...
Conflict of Interest:
None declared. - Published on: 22 March 2016Bevacizumab and rodent VEGFShow More
Dear Editor,
We read with interest the recently published paper by Manzano et al. titled ‘Inhibition of experimental corneal neovascularisation by bevacizumab (Avastin)’. The authors used topical eyedrop application of either saline or bevacizumab in a rat model of corneal neovascularization, with apparent moderate success. Furthermore, in their discussion, they mention that there was incomplete inhibition of th...
Conflict of Interest:
None declared.