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Comparison of anterior chamber depth measurements using the IOLMaster, scanning peripheral anterior chamber depth analyser, and anterior segment optical coherence tomography
  1. Raghavan Lavanya1,
  2. Livia Teo1,
  3. David S Friedman3,
  4. Han T Aung2,
  5. Mani Baskaran2,
  6. Hong Gao5,
  7. Tamuno Alfred5,
  8. Steve K Seah1,
  9. Kenji Kashiwagi6,
  10. Paul J Foster7,
  11. Tin Aung8
  1. 1Singapore National Eye Centre, Singapore
  2. 2Singapore Eye Research Institute, Singapore
  3. 3Wilmer Eye Institute and Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
  4. 4Medical and Vision Research Foundation, Sankara Nethralaya, Chennai, India
  5. 5Clinical Trials and Epidemiology Research Unit, Singapore
  6. 6University of Yamanashi, Chuo Yamanashi, Japan
  7. 7Institute of Ophthalmology and Moorfields Eye Hospital, London, UK
  8. 8National University of Singapore, Singapore
  1. Correspondence to: Associate Professor Tin Aung Glaucoma Department, Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore 168751; tin11{at}pacific.net.sg

Abstract

Aim: To compare anterior chamber depth measurements by three non-contact devices—the IOLMaster, scanning peripheral anterior chamber depth analyser (SPAC), and Visante anterior segment optical coherence tomography (AS-OCT)

Methods: Prospective, cross sectional study of 497 phakic subjects over 50 years of age attending a community clinic in Singapore. Anterior chamber depth of the right eye was measured using all three techniques by the same investigator. Depth measurements were made from the corneal epithelium to the anterior lens surface. The values obtained were compared using Bland–Altman analysis.

Results: 232 men and 265 women were examined (mean (SD) age, 63.4 (7.9) years). Mean anterior chamber depth was 3.08 (0.36) mm with IOLMaster, 3.10 (0.44) mm with SPAC, and 3.14 (0.34) mm with AS-OCT. A significant difference was present between the anterior chamber depth measurements recorded by the three devices (p<0.0001). Mean differences between the measurements were: AS-OCT v IOLMaster, 0.062 (0.007) mm (95% limits of agreement, −0.37 to 0.25 mm) (p<0.0001); AS-OCT v SPAC, 0.035 (0.011) mm (−0.44 to 0.51 mm) (p = 0.0001); SPAC v IOLMaster, 0.027 (0.012) mm (−0.57 to 0.50 mm) (p = 0.027).

Conclusions: AS-OCT gave systematically deeper anterior chamber measurements than SPAC and IOL-Master. However, as the differences found were small they are unlikely to be clinically important.

  • AS-OCT, anterior segment optical coherence tomography
  • IOL, intraocular lens
  • PCI, partial coherence interferometry
  • SPAC, scanning peripheral anterior chamber depth analyser
  • anterior chamber depth
  • biometry
  • anterior segment
  • angle closure
  • optical coherence tomography
  • AS-OCT, anterior segment optical coherence tomography
  • IOL, intraocular lens
  • PCI, partial coherence interferometry
  • SPAC, scanning peripheral anterior chamber depth analyser
  • anterior chamber depth
  • biometry
  • anterior segment
  • angle closure
  • optical coherence tomography

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Footnotes

  • Published Online First 27 February 2007

  • Conflict of interest: KK has a Japanese patent on SPAC (Japanese patent No 3878164). DSF has been a paid consultant to Carl Zeiss-Meditec. TA has received research funding and travel support from Carl Zeiss Meditec.

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