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Management of intraoperative tilting of the scleral-fixated intraocular lens in classical aniridia
  1. Hemamalini Arvind1,
  2. Alex Hunyor1,
  3. Kathy McClellan1,
  4. Francis Billson1,
  5. John Grigg1,
  6. Robyn Jamieson2,3
  1. 1
    Sydney Eye Hospital, University of Sydney, New South Wales, Australia
  2. 2
    The Children’s Hospital at Westmead, New South Wales, Australia
  3. 3
    Dr H Arvind, Save Sight Institute, Sydney Eye Hospital, 8, Macquarie Street, Sydney, NSW 2000, Australia;
    hemamalini_arvind@yahoo.com

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    Scleral-fixated posterior chamber intraocular lenses (SFIOL) are an attractive option for optical correction of aphakia in people with ectopia lentis. Postoperative intraocular lens (IOL) tilt/decentration have been reported in 5–10% of eyes that undergo SFIOL implantation.1 2 We report the case of a boy with aniridia who underwent SFIOL implantation and had intraoperative IOL tilting, and the management of intraoperative tilting.

    Case report

    A 16-year-old boy had been diagnosed at 4 weeks of age to have bilateral aniridia with almost completely absent irides, ectopia lentis, anterior polar cataracts, macular hypoplasia and nystagmus. Sequence analysis of the coding exons of the PAX6 gene revealed a C→T variant at nucleotide 1017 of the cDNA M93650 (http://pax6.hgu.mrc.ac.uk/About/pax6cdna.htm). This novel …

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