Expression of p27(KIP1) and cyclin D1, and cell proliferation in human pterygium

We would like to thank Kase et al for their interesting report1 on p27 and cyclin expression in pterygium. The authors have reported in table 11 that cyclin D was upregulated and p27 downregulated in pterygium, and concluded that a disorder of epithelial cell proliferation or cell cycle was involved. However, several important issues have not been addressed. We would like to highlight three points:

1. p27 is usually regarded …