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The natural history of OPA1-related autosomal dominant optic atrophy
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    Spontaneous visual improvement in dominant optic atrophy

    Dear Editor:

    I read with interest the article by Dr. Cohn, et al regarding the natural history of autosomal dominant optic atrophy (DOA). The authors describe an average of 10-year follow up for 69 patients with genetically confirmed DOA. In their study, 6 (9%) patients enjoyed improvement in visual acuity by 2 or more lines.

    I found this surprising, and I wonder if the authors could provide...

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    Conflict of Interest:
    None declared.