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Br J Ophthalmol 2008;92:1342-1346 doi:10.1136/bjo.2007.133041
  • Original Article
    • Clinical science

Clinical spectrum of lamellar macular defects including pseudoholes and pseudocysts defined by optical coherence tomography

This article has been UnlockedFree via Creative Commons: OPEN ACCESS
  1. J C Chen1,2,
  2. L R Lee1,3
  1. 1
    City Eye Centre, Brisbane, Australia
  2. 2
    Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia
  3. 3
    Department of Ophthalmology, University of Queensland, Royal Brisbane Hospital, Brisbane, Australia
  1. Dr J Chen, City Eye Centre, 10/135 Wickham Terrace, Brisbane Q 4000, Australia; eye{at}cityeye.com.au
  • Accepted 11 June 2008
  • Published Online First 6 August 2008

Abstract

Objective: To present the clinical spectrum of lamellar macular defects and describe the different subtypes based on their optical coherence tomography (OCT) configuration and visual prognosis.

Methods: The retrospective observational case series reviewed OCT scans of 92 eyes with lamellar macular defects. Lamellar macular defects were categorised into subtypes of macular pseudohole (MPH), lamellar macular hole (LMH) and foveal pseudocyst (FP) according to their OCT morphology. The defects were quantitatively characterised in terms of base diameter, depth and central foveal thickness, and examined for the presence of associated epiretinal membranes (ERM).

Results: Visual acuity (VA) was significantly correlated with the central foveal thickness and depth of the lamellar defect. MPH was associated with better VA compared with LMH and FP. MPH was of a smaller base diameter and had a greater central foveal thickness than that of LMH and FP. Fifty-per cent of all lamellar defects had an associated ERM.

Conclusions: Different profiles of lamellar macular defects were characterised and quantified by OCT. Deeper and wider lamellar defects were associated with poorer visual outcome. Such objective parameters lamellar macular defects are of value when explaining to patients regarding their decreased acuity. Future prospective investigations are required to study the natural history of lamellar defects of different aetiology and surgical indications.

Footnotes

  • Competing interests: None.

  • Ethics approval: Ethics approval was provided by Queensland University of Technology Human Research Ethics Committee.

  • Patient consent: Obtained.

  • This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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