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Features of age-related macular degeneration assessed with three-dimensional Fourier-domain optical coherence tomography
  1. M N Menke1,
  2. S Dabov2,
  3. V Sturm1
  1. 1
    University of Zürich, Department of Ophthalmology, Zürich, Switzerland
  2. 2
    University of Münster, School of Medicine, Münster, Germany
  1. Dr M N Menke, Department of Ophthalmology, University of Zürich (USZ), Frauenklinikstrasse 24, 8091 Zürich, Switzerland; marcel.menke{at}gmail.com

Abstract

Background/aims: Age-related macular degeneration (AMD) is among the leading causes of severe visual loss in individuals over 60 years old. Retinal changes associated with AMD were previously studied by time-domain optical coherence tomography (OCT). Recently, Fourier-domain OCT (FD-OCT) has been introduced. FD-OCT provides increased scan resolution and scanning speed, and generates three-dimensional (3D) OCT images. The purpose of this study was to demonstrate features of AMD assessed with high-density scanning 3D-FD-OCT (Topcon 3D-OCT1000).

Methods: The study was designed as a prospective, observational case series. Five patients with typical morphological changes due to AMD were chosen based on funduscopic findings. Eyes with non-exudative- and exudative AMD were included. 3D-FD-OCT images were obtained, and typical morphological changes associated with AMD were presented.

Results: FD-OCT provided detailed 3D-images of retinal structure. In addition, FD-OCT showed improved retinal coverage and image quality. FD-OCT B-scan imaging identified typical retinal changes associated with AMD. In addition, FD-OCT imaging revealed information about the extent and the 3D shape of retinal lesions.

Conclusion: 3D-FD-OCT imaging is useful for diagnosing and following patients with AMD. In addition, 3D-FD-OCT provided information about the extent and 3D shape of retinal pathologies and showed improved retinal coverage.

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Footnotes

  • Competing interests: None.

  • Ethics approval: Ethics approval was provided by the Institutional Review Board of the University Hospital Zurich.

  • Patient consent: Obtained.

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