rss
Br J Ophthalmol 2008;92:1492-1497 doi:10.1136/bjo.2008.141242
  • Original Article
    • Clinical science

Features of age-related macular degeneration assessed with three-dimensional Fourier-domain optical coherence tomography

  1. M N Menke1,
  2. S Dabov2,
  3. V Sturm1
  1. 1
    University of Zürich, Department of Ophthalmology, Zürich, Switzerland
  2. 2
    University of Münster, School of Medicine, Münster, Germany
  1. Dr M N Menke, Department of Ophthalmology, University of Zürich (USZ), Frauenklinikstrasse 24, 8091 Zürich, Switzerland; marcel.menke{at}gmail.com
  • Accepted 24 July 2008
  • Published Online First 14 August 2008

Abstract

Background/aims: Age-related macular degeneration (AMD) is among the leading causes of severe visual loss in individuals over 60 years old. Retinal changes associated with AMD were previously studied by time-domain optical coherence tomography (OCT). Recently, Fourier-domain OCT (FD-OCT) has been introduced. FD-OCT provides increased scan resolution and scanning speed, and generates three-dimensional (3D) OCT images. The purpose of this study was to demonstrate features of AMD assessed with high-density scanning 3D-FD-OCT (Topcon 3D-OCT1000).

Methods: The study was designed as a prospective, observational case series. Five patients with typical morphological changes due to AMD were chosen based on funduscopic findings. Eyes with non-exudative- and exudative AMD were included. 3D-FD-OCT images were obtained, and typical morphological changes associated with AMD were presented.

Results: FD-OCT provided detailed 3D-images of retinal structure. In addition, FD-OCT showed improved retinal coverage and image quality. FD-OCT B-scan imaging identified typical retinal changes associated with AMD. In addition, FD-OCT imaging revealed information about the extent and the 3D shape of retinal lesions.

Conclusion: 3D-FD-OCT imaging is useful for diagnosing and following patients with AMD. In addition, 3D-FD-OCT provided information about the extent and 3D shape of retinal pathologies and showed improved retinal coverage.

Footnotes

  • Competing interests: None.

  • Ethics approval: Ethics approval was provided by the Institutional Review Board of the University Hospital Zurich.

  • Patient consent: Obtained.

This Article

  1. Abstract
  2. Full text
  3. PDF
  4. All versions of this article:
    1. bjo.2008.141242v1
    2. 92/11/1492 most recent

Responses

  1. Submit a response
  2. No responses published

Register for free content

The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.