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Capnocytophaga canimorsus endogenous endophthalmitis in an immunocompetent host
  1. T G Papadaki1,
  2. R el Moussaoui2,
  3. R J van Ketel3,
  4. F D Verbraak1,
  5. H S Tan1
  1. 1
    Department of Ophthalmology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
  2. 2
    Department of Internal Medicine, Division of Infectious Diseases, Tropical Medicine and AIDS, and Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
  3. 3
    Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
  1. Dr H S Tan, Department of Ophthalmology, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands; h.tan{at}amc.uva.nl

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Capnocytophaga is an opportunistic pathogen that is normally found in the oral flora of humans and animals.1 Ocular Capnocytophaga infection involves most commonly the cornea.2 We describe a case of bilateral, endogenous Capnocytophaga canimorsus endophthalmitis in a healthy patient.

A 60-year-old Caucasian male was admitted for high fever (41°C), diarrhoea and vomiting. The physical exam disclosed urticaria dermatitis, active herpes labialis and uveitis right eye (OD). Baseline laboratory investigations revealed an increased white blood count with lymphopenia, moderately elevated liver enzymes, dehydration and increased C-reactive protein. An autoimmune disease was presumed, and the patient was administered high-dose prednisolone (60 mg/day) and prophylactic acyclovir (Zelitrex 500 mg tablets four times daily). Three days later, the vision deteriorated significantly, and the patient was …

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