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Br J Ophthalmol 2008;92:1599-1600 doi:10.1136/bjo.2007.132902
  • Education

Presumptive Jamestown Canyon viral retinitis

  1. M M K Muqit1,
  2. H Devonport1,
  3. R A Smith2,
  4. B Dhillon3
  1. 1
    Uveitis Service, Department of Ophthalmology, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK
  2. 2
    Department of Radiology, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK
  3. 3
    Princess Alexandra Eye Pavilion, Edinburgh, UK
  1. Mr M M K Muqit, Department of Ophthalmology, Bradford Teaching Hospitals NHS Foundation Trust, Duckworth Lane, Bradford BD9 6RJ, UK; mmmk3{at}aol.com
  • Accepted 2 February 2008

A 60-year-old Caucasian man presented with unilateral vitritis and retinitis. HIV was subsequently diagnosed, and the CD4+ count was high at 260 cells/μl. Serological, aqueous and vitreous testing for cytomegalovirus (CMV) and herpes viruses were normal. The patient was treated for presumed CMV retinitis with intravitreal ganciclovir and oral valganciclovir, but there was no response to therapy. After 6 months, the vitritis and retinitis persisted, and the CD4+ count remained at 210 cells/μL. Highly active antiretroviral therapy (HAART) was commenced, and the retinitis resolved over the following two months. The patient subsequently developed a homonymous hemianopic …

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