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B cell monoclonal gene rearrangements have been reported in several cases of primary intraocular lymphoma and primary central nervous system lymphomas. Such molecular analysis has been performed on only one case of a primary testicular and a metastatic intraocular lymphoma. However, the gene rearrangements differed at the two sites. We present a case in which B cell monoclonality was found in an intraocular lymphoma and a primary breast lymphoma. Intraocular non-Hodgkin’s lymphomas are uncommon malignant tumours derived from two types of lymphomas; a primary central nervous system lymphoma (PCNSL) and a systemic lymphoma. Compared with primary intraocular lymphomas (PIOLs), the prevalence of metastatic systemic lymphomas is much lower.1 2 The diagnosis of …
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