Table 2 Virological analysis and ocular findings after treatment of patients with varicella zoster virus (VZV) anterior uveitis
| Case | VZV DNA(copies/ml) | Final ocular findings | Iris atrophy | Extentof irisatrophy(%) | Pupil | Maximumpupildiameter(mm) | Systemictreatment | Follow-up(months) | |||
| VA | IOP(mm Hg) | Cellsin AC | Flarein AC | ||||||||
| 1 | 1.2×107 | mm | 10 | – | 13 | Wide | 40 | Distorted, mydriasis | 8.1 | ACV, ACZ | 48 |
| 2 | 1.2×106 | 0.9 | 14 | – | 8 | Segmental | 4 | Distorted, mild mydriasis | 3.4 | VCV, ACZ | 5 |
| 3 | 1.0×106 | 0.8 | 7 | – | 5 | Segmental | 15 | Distorted, mydriasis | 5.0 | VCV | 4 |
| 4 | 9.8×105 | 0.9 | 10 | – | 73 | Segmental | 20 | Distorted, mydriasis | 7.9 | VCV | 12 |
| 5 | 9.8×105 | 0.8 | 20 | – | 22 | Segmental | 29 | Distorted, mydriasis | 7.0 | VCV | 5 |
| 6 | 1.3×105 | 1.5 | 13 | – | 6 | Circular | 1 | Normal | 2.6 | ACV | 26 |
| 7 | 2.2×104 | 2 | 16 | – | 3 | Circular | 1 | Distorted, mild mydriasis | 4.3 | VCV | 13 |
| 8 | 3.8×102 | 1.2 | 12 | – | 9 | None | 0 | Normal | 2.6 | ACV, ACZ | 4 |
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The copy number of the VZV genome in aqueous humor was evaluated with real-time PCR. The extent of iris atrophy was calculated using Photoshop Elements V2.0.
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ACV, aciclovir; ACZ, acetazolamide; mm, motus manus; VCV, valaciclovir.
