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Marginal zone lymphomas (MZL), clearly defined in the WHO classification of lymphoid neoplasms,1 comprise three distinct entities depending on the site of involvement: extranodal MZL or mucosa associated lymphoid tissue (MALT) type, splenic MZL (with or without villous lymphocytes) and nodal MZL. Lacrimal gland and intraorbital sites are the most frequent ophthalmological sites of MALT-type ocular adnexal lymphomas (OAL).2 We report the unusual case of a patient with bilateral intraorbital MALT-type lymphoma with MZL cells in the peripheral blood and ophthalmologic large B cell lymphoma histological transformation at the time of initial diagnosis.
A 60-year-old woman with a history …
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