rss
Br J Ophthalmol 92:655-660 doi:10.1136/bjo.2007.134429
  • Clinical science
    • Original Article

Photodynamic therapy with verteporfin in paediatric and young adult patients: long-term treatment results of choroidal neovascularisations

Table 1 Patient and lesion characterisics of the subgroups presumed ocular histoplasmosis syndrome (POHS) (n = 9), multifocal choroiditis and panuveitis/toxoplasmosis (n = 4) and myopia (n = 3)
Pt. no. Gender Eye CNV location CNV type CNV cause Follow-up (months) Age (years) PDT (no.) Log(MAR) ΔVA (lines) PLD pre (μm) PLD last (μm) GLD pre (μm) GLD last (μm) CLD pre (μm)
VA pre VA last
1 F OD, B Subfov Class POHS 18 11 3 0.7 0.3 4 1800 1800 1800 800 1800
2 F OS Juxtafov Class POHS 19 23 3 0.6 0.4 2 1400 2400 1400 2400 1400
3 F OS, B Subfov Class POHS 3 29 1 0.6 0.8 −2 2100 3000 4600 1600 2100
4 F OD Subfov Class POHS 18 8 1 1.5 1.0 3 3800 5400 3800 3800 3800
5 F OD Subfov Class POHS 18 29 1 0.3 0.0 2 850 1200 900 600 900
6 F OD Subfov Class POHS 6 24 1 0.9 0.7 2 2000 2500 3000 2500 2000
7 F OD Subfov Class POHS 85 6 2 1.0 0.5 6 3800 4100 3800 4100 4000
8 F OS Subfov Class POHS 62 28 1 0.5 0.0 5 1100 2780 1900 1900 1100
9 M OD Subfov Class POHS 23 18 2 1.0 0.7 3 800 1500 800 600 800
10 M OS, B Subfov Class Myopia 23 13 3 0.8 0.6 2 2600 2700 800 900 800
11 F OS Subfov Class Myopia 80 31 1 0.5 0.3 2 1700 2800 2000 1500 1200
12 M OS, B Extrafov Class myopia 35 15 1 0.2 0.0 2 1100 1100 1000 600 900
n = 12 Mean (SD) 32 (28) 19.9 (8.8) 1.7 (0.9) 0.76 (0.31) 0.48** (0.30) 2.6 (1.9) 1921 (985) 2607** (1171) 2150 (1274) 1775 (1169) 1733 (1062)
13 F OS Subfov Class Toxo 59 10 5 0.3 0.3 0 2600 4000 3200 2200 2300
14 F OD Extrafov Class Toxo 23 13 2 0.3 0.3 0 1500 2800 3200 1100 1700
15* M OS Subfov Class MCP 27 30 4 0.2 0.7 −5 900 3300 900 1800 900
16† M OS Subfov Class MCP 41 28 4 0.4 1.5 −11 500 4000 800 4000 500
n = 16 Mean (SD) 34 (24) 19.7 (8.7) 2.2 (1.3) 0.60 (0.35) 0.49 (0.39) 1.1 (4.1) 1722 (864) 2836** (1118) 2119 (1251) 1963 (1387) 1625 (1300)
  • Mean values (SD) are indicated in bold. Mean values of the total cohort (n = 16) are shown below.

  • *Patient 15 received systemic steroid treatment during 3 months after first PDT.

  • †Patient 16 received long-term systemic steroid treatment and one intravitreal injection the day after first PDT.

  • **p>0.05 (paired two-sided Student t test).

  • B, bilateral choroidal neovascularisation; class, classic CNV subtype; CLD, neovascularisation lesion dimension; CNV, choroidal neovascularisation; fov, foveal; GLD, greatest linear lesion dimension; M/F, male/female; OD/OS, study eye, oculus dexter/sinister; PLD, pigment epithelial lesion dimension; Pt. no., patient number; Toxo, toxoplasmosis; VA, visual acuity.

This Article

Register for free content


Free sample
This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of BJO.
View free sample issue >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.