rss
Br J Ophthalmol 2008;92:906-911 doi:10.1136/bjo.2007.129825
  • Original Article

Relationship between retinal nerve fibre layer measurements and retinal sensitivity by scanning laser polarimetry with variable and enhanced corneal compensation

  1. J Choi1,2,
  2. K H Kim2,
  3. C H Lee2,
  4. H Cho3,
  5. K R Sung2,
  6. J Y Choi1,
  7. B-J Cho1,
  8. M S Kook2
  1. 1
    HanGil Eye Hospital, Incheon, Republic of Korea
  2. 2
    Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Republic of Korea
  3. 3
    Department of Ophthalmology, The Armed Forces Capital Hospital, Seongnam, Republic of Korea
  1. Dr M S Kook, Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, 388-1 Pungnap-2-dong, Songpa-gu, Seoul, Korea 138-736; mskook{at}amc.seoul.kr
  • Accepted 6 April 2008

Abstract

Aim: To evaluate the relationship between retinal sensitivity and the retinal nerve fibre layer (RNFL) measurements by scanning laser polarimetry (SLP) with variable corneal compensation (VCC) and enhanced corneal compensation (ECC) in a homogenous group of Asian eyes.

Methods: The presence of atypical birefringence pattern (ABP) on the peripapillary SLP-VCC was determined by the subjective evaluation and the objective criteria of software-provided typical scan score (TSS) <80. RNFL parameters were measured by both VCC and ECC techniques, and the visual field was examined. The relationships between retinal sensitivity and RNFL measurements were sought globally and regionally with linear and logarithmic regression analysis. Coefficients of the determination for VCC and ECC techniques were compared.

Results: Seventy-two eyes were classified as having normal birefringence pattern (NBP) and 53 eyes were classified as having ABP. In eyes with ABP, R2 values for the association between retinal sensitivity and RNFL measurements were 0.06–0.24 with VCC, whereas they were 0.21–0.48 with ECC. In eyes with NBP, R2 values for the association between retinal sensitivity and RNFL measurements were 0.14–0.35 with VCC, whereas they were 0.22–0.43 with ECC. The association of RNFL measurements with retinal sensitivity was significantly better with ECC than with VCC in nine out of 16 regression models in eyes with ABP, whereas only three models showed better associations with ECC in eyes with NBP (p<0.05).

Conclusions: The associations of RNFL measurements on the routine SLP printouts with corresponding retinal sensitivity were stronger with the ECC algorithm compared with VCC in Asian eyes with ABP.

Footnotes

  • Funding: None.

  • Competing interests: None declared.

  • Ethics approval: This study was approved by the institutional review board of the Asan Medical Center and adhered to the Declaration of Helsinki. Informed consent was obtained from each subject.

This Article

  1. Abstract
  2. Full text
  3. PDF

Responses

  1. Submit a response
  2. No responses published

Register for free content

The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.