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Br J Ophthalmol 2008;92:1034 doi:10.1136/bjo.2007.127522
  • Education

Sustained remission after infliximab in a child with vasculitis refractory to conventional immunosuppressives including interferon-α

  1. C Evereklioglu1,
  2. M Borlu2
  1. 1
    Department of Ophthalmology, Division of Uvea-Behçet Unit, Erciyes University Medical Faculty, Kayseri, Turkey
  2. 2
    Department Dermatology, Erciyes University Medical Faculty, Kayseri, Turkey
  1. Dr C Evereklioglu, Sivas Cad Cebeci Apt A-Blok 175/15, TR-38020, Kayseri, Turkey; evereklioglu{at}hotmail.com
  • Accepted 31 January 2008

We report a 15-year-old Caucasian girl with longstanding sight-threatening bilateral uveitis who did not respond to intensive treatment with corticosteroids, azathioprine, ciclosporin and interferon over months with a progressive deterioration of vision in both eyes. She developed recurrent anterior chamber hypopyon formation, even when under the given medications. She had a rapid and dramatic response to treatment with infliximab, and long-term remission was obtained by continuous 24-month treatment with repeated infliximab infusions. This case highlights the role of anti-tumour necrosis factor …

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