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Abnormal fundus autofluorescence patterns in myopic choroidal neovascularisation
  1. M Sawa,
  2. F Gomi,
  3. M Tsujikawa,
  4. Y Ikuno,
  5. H Sakaguchi,
  6. K Sayanagi,
  7. Y Tano
  1. Department of Ophthalmology, Osaka University Medical School, Japan
  1. Dr M Sawa, Department of Ophthalmology, Osaka University Medical School, Japan, Room E7, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan; sawamiki{at}ophthal.med.osaka-u.ac.jp

Abstract

Background/aims: To investigate fundus autofluorescence (FAF) findings in eyes with myopic choroidal neovascularisation (CNV).

Methods: Observational case series. Twenty-seven consecutive eyes with CNV for at least 1 year were included. FAF patterns, time after the onset of CNV seen on FAF and FAF changes were evaluated.

Results: The following patterns were observed: pattern I (n = 2), relative hypoautofluorescence around the CNV surrounded by hyperautofluorescence a mean of 17 months after CNV onset; pattern II (n = 11), small lobular or multilobular well-defined FAF defects within a relatively hypoautofluorescent region surrounded by hyperautofluorescence a mean of 35 months after onset; pattern III (n = 4), large lobular or multilobular well-defined FAF defects surrounded by hyperautofluorescence a mean of 59 months after onset; and pattern IV (n = 10), large lobular or crescent-shaped well-defined FAF defects a mean of 107 months after onset. Well-defined FAF defects corresponded to chorioretinal atrophy on colour fundus photographs. During the follow-up period, two eyes with pattern I evolved into pattern II. Lobular or multilobular well-defined FAF defects enlarged in 11 eyes (pattern II, nine eyes; pattern III, two eyes).

Conclusion: Autofluorescent changes progress over time through pattern grading. A pattern classification might be helpful to predict chorioretinal atrophy changes around myopic CNV.

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Footnotes

  • Funding: Supported by a research grant 18791276 from the Japan Society for the Promotion of Science, Tokyo, Japan.

  • Competing interests: None.

  • Ethics approval: Ethics approval was obtained from the institutional review board of Osaka University Medical School Hospital.

  • Patient consent: Obtained.

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