rss
Br J Ophthalmol 2008;92:1236-1240 doi:10.1136/bjo.2008.138198
  • Original Article
    • Clinical science

Abnormal fundus autofluorescence patterns in myopic choroidal neovascularisation

  1. M Sawa,
  2. F Gomi,
  3. M Tsujikawa,
  4. Y Ikuno,
  5. H Sakaguchi,
  6. K Sayanagi,
  7. Y Tano
  1. Department of Ophthalmology, Osaka University Medical School, Japan
  1. Dr M Sawa, Department of Ophthalmology, Osaka University Medical School, Japan, Room E7, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan; sawamiki{at}ophthal.med.osaka-u.ac.jp
  • Accepted 4 June 2008
  • Published Online First 10 July 2008

Abstract

Background/aims: To investigate fundus autofluorescence (FAF) findings in eyes with myopic choroidal neovascularisation (CNV).

Methods: Observational case series. Twenty-seven consecutive eyes with CNV for at least 1 year were included. FAF patterns, time after the onset of CNV seen on FAF and FAF changes were evaluated.

Results: The following patterns were observed: pattern I (n = 2), relative hypoautofluorescence around the CNV surrounded by hyperautofluorescence a mean of 17 months after CNV onset; pattern II (n = 11), small lobular or multilobular well-defined FAF defects within a relatively hypoautofluorescent region surrounded by hyperautofluorescence a mean of 35 months after onset; pattern III (n = 4), large lobular or multilobular well-defined FAF defects surrounded by hyperautofluorescence a mean of 59 months after onset; and pattern IV (n = 10), large lobular or crescent-shaped well-defined FAF defects a mean of 107 months after onset. Well-defined FAF defects corresponded to chorioretinal atrophy on colour fundus photographs. During the follow-up period, two eyes with pattern I evolved into pattern II. Lobular or multilobular well-defined FAF defects enlarged in 11 eyes (pattern II, nine eyes; pattern III, two eyes).

Conclusion: Autofluorescent changes progress over time through pattern grading. A pattern classification might be helpful to predict chorioretinal atrophy changes around myopic CNV.

Footnotes

  • Funding: Supported by a research grant 18791276 from the Japan Society for the Promotion of Science, Tokyo, Japan.

  • Competing interests: None.

  • Ethics approval: Ethics approval was obtained from the institutional review board of Osaka University Medical School Hospital.

  • Patient consent: Obtained.

This Article

  1. Abstract
  2. Full text
  3. PDF
  4. All versions of this article:
    1. bjo.2008.138198v1
    2. 92/9/1236 most recent

Responses

  1. Submit a response
  2. No responses published

Register for free content

The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.