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Br J Ophthalmol 92:1275-1282 doi:10.1136/bjo.2008.138768
  • Original Article
    • Laboratory science

Conjunctival and corneal reactions in rabbits following short- and repeated exposure to preservative-free tafluprost, commercially available latanoprost and 0.02% benzalkonium chloride

Table 2 Description of cresyl violet impression cytology at 4 h
Phosphate-buffered saline Preservative-free tafluprost Latanoprost 0.02% benzalkonium chloride
Nucleo:cytoplasmic ratio 1:2–1:3 1:2–1:3 Cell borders not clear No epithelial cells visible
Ratio non-applicable
Anisocytosis/anisonucleocytosis – + +++ No epithelial cells visible
Cell size Normal Normal Very irregular Non-applicable
Inflammatory cells – ++ ++++ ++++
Goblet cells Normal Normal Goblet cell imprint, no more complete cell Could not been seen
Goblet cells:epithelial cells ratio, % 14 15 0 0

  • –, no abnormality; +, discrete; ++, moderate; +++, important; ++++, extremely intense.

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