We greatly appreciate the recent response to our article by Wang et al entitled “Management of angle closure glaucoma in East Asian eyes: a response to Argon laser iridotomy-induced bullous keratopathy—a growing problem in Japan,” in which they reaffirmed the need to address the worrying increase in ocular decomposition resulting from argon laser iridotomy (ALI)-induced complications in Asian countries. It has long been believed that ALI does not change corneal endothelial cell density;1 2 however, that does not seem to be correct in eyes with a pigmented iris. As was noted in our recent article,3 …