Objective: To compare the long-term outcomes of photorefractive keratectomy (PRK) and laser in situ keratomilesis (LASIK) for myopia between −6 and −10 D.
Methods: A retrospective, control-matched study including 68 eyes, 34 which underwent PRK and 34 LASIK, with myopia between −6 and −10 D, operated using the VISX 20/20 excimer laser, was performed. Optical zones of 5.5 to 6 mm were used. All PRK-treated eyes were matched with LASIK-treated eyes of the same age, spherical equivalent within ±1.25 D, sphere within ±1.5 D and cylinder within ±2.5 D. All patients were evaluated 3 months, 1 year, 2 years, 5 years and 10 years after surgery. The main outcomes measures were refractive predictability and stability, safety, efficacy and re-treatment rate.
Results: At 10 years, 20 (71%) and 23 (88%) were within ±1.00 D after PRK and LASIK respectively. The re-treatment rate was 35% and 18% respectively. No eye lost more than two lines of BSCVA in both groups. The efficacy was 0.90 for PRK and 0.95 for LASIK.
Conclusions: Both PRK and LASIK were safe for moderate myopia. LASIK demonstrated slightly better efficacy, predictability, and less rate of re-treatment after 10 years. The technical improvements should be taken into account when comparing these results with those obtained more recently.
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Funding This study has been supported in part by a grant of the Spanish Ministry of Health, Instituto Carlos III, Red Temática de Investigación en Oftalmología, Subproyecto de Cirugía Refractíva y Calidad Visual (C03/13).
Competing interests None.
Provenance and Peer review Not commissioned; externally peer reviewed.
Ethics approval Ethics approval was provided by the institutional review board (Ethical Committee of Clinical Investigation of Instituto Oftalmológico de Alicante).