rss
Br J Ophthalmol 2009;93:1410-1411 doi:10.1136/bjo.2009.158949
  • PostScript
  • Letter

Tachosil: a new alternative for the treatment of non-traumatic corneal perforations

  1. M Hurtado-Sarrió1,
  2. A Duch-Samper2,
  3. A Cisneros-Lanuza1,
  4. M Díaz-Llopis1
  1. 1
    Ophthalmology Service, La Fe University Hospital, Valencia, Spain
  2. 2
    Ophthalmology Service, Arnau de Vilanova Hospital, Valencia, Spain
  1. Correspondence to Dr M Hurtado-Sarrió, Ophthalmology Service, La Fe University Hospital, Valencia, Spain, Esmeralda I, Casa 7, Mas Camarena, 46117 Betera, Valencia, Spain; hurtado_mer{at}gva.es
  • Accepted 21 March 2009

TachoSil is a collagen sponge with human fibrinogen 5.5 mg, and human thrombin 2.0 IU.

Upon contact with physiological fluids or saline solution, the components of the coating dissolve and partly diffuse into the wound surface, creating a firm, mechanically stable network with good adhesive properties as well as sealing. Here we report the first case of the use of a collagen sponge combined with human fibrin sealant (TachoSil) in ophthalmology to patch a corneal perforation after infectious keratitis.

Case report

An 84-year-old Caucasian male with a history of heart disease treated with acenocoumarin and chronic obstructive pulmonary disease (COPD) reported to the emergency room with red eye, ocular pain, photophobia, decreased vision and discharge. At the slit-lamp examination, a large corneal stromal infiltrate with hypopyon was observed. A bacterial culture revealed Streptococcus pneumoniae. The keratitis responded to …

This Article

Services

  1. Request permissions

Responses

  1. Submit a response
  2. No responses published

Social bookmarking

Register for free content


Free sample
This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of BJO.
View free sample issue >>

Free archive
The full back archive is now available for BJO. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006, back to volume 1 issue 1.
Register to access the free archive >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.