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Br J Ophthalmol 93:1535-1538 doi:10.1136/bjo.2008.156828
  • Original Article

Turnover rate of tear-film lipid layer determined by fluorophotometry

Table 1

Turnover rates of a topically applied (1 μl) 50 mg/ml 5-dodecanoylaminofluorescein (DAF) emulsion or 50 μg/ml fluorescein sodium solution observed in 12 subjects

Subject no Turnover rate (%/min)
DAF Fluorescein sodium
1 0.51 5.2
2 0.46 4.4
3 0.54 7.1
4 0.61 7.2
5 0.84 9.7
6 0.93 10.0
7 0.84 10.2
8 1.12 11.5
9 1.60 14.7
10 1.31 12.9
11 1.24 15.8
12 1.14 14.5
Mean (SD) 0.93 (0.36) 10.3 (3.7)
  • The turnover rate of DAF was significantly lower than that of fluorescein sodium (p<0.05).

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