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Limits of the retinal-mapping program in age-related macular degeneration
  1. P A Keane1,
  2. S Liakopoulos2,
  3. A C Walsh3,
  4. S R Sadda3
  1. 1
    Doheny Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA
  2. 2
    Department of Vitreoretinal Surgery, Center for Ophthalmology, University of Cologne, Germany
  3. 3
    Doheny Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA
  1. Dr S R Sadda, Doheny Eye Institute, Keck School of Medicine of the University of Southern California, 1450 San Pablo Street, DEI 3623, Los Angeles, CA 90033, USA; sadda{at}usc.edu

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We read with interest the recent study by Krebs et al demonstrating the limitations of StratusOCT mapping software in the context of age-related macular degeneration (AMD).1 We wish to applaud the authors for their study—while the limitations of StratusOCT automated analysis have previously been reported,2 the fact remains that many ophthalmologists may not be well acquainted with these errors. We agree with the authors and wish to underline the importance of these errors in this era of optical coherence tomography (OCT)-guided retreatment regimens for anti-angiogenic agents and increasing adoption of quantitative OCT measurements as secondary outcome parameters in clinical trials.3

In their study, the authors present evidence that automated Stratus software provides correct results in only 57.1% of eyes with AMD. …

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