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Br J Ophthalmol 93:316-321 doi:10.1136/bjo.2007.135111
  • Clinical science
    • Original Article

Conjunctival hyperaemia with the use of latanoprost versus other prostaglandin analogues in patients with ocular hypertension or glaucoma: a meta-analysis of randomised clinical trials

Table 2 Sensitivity analysis of the association of conjunctival hyperaemia and the use of latanoprost, travoprost and bimatoprost
Latanoprost vs bimatoprost
Statistical model No of studies No of patients OR (95% CI)
Fixed effects 8 1240 0.32 (0.24 to 0.42)
Random effects 8 1240 0.32 (0.24 to 0.42)
Analyses excluding
    Dubiner et al25 7 1197 0.31 (0.24 to 0.41)
    Gandolfi et al24 7 1008 0.33 (0.24 to 0.44)
    Noecker et al26 7 971 0.32 (0.23 to 0.44)
    Parrish et al32 7 968 0.29 (0.21 to 0.40)
    Walters et al27 7 1164 0.32 (0.24 to 0.43)
    Konstas et al28 7 1198 0.33 (0.25 to 0.43)
    Dirks et al29 7 1180 0.32 (0.24 to 0.42)
    Konstas et al30 7 994 0.34 (0.25 to 0.45)
Latanoprost vs travoprost
Statistical model No of studies No of patients OR (95% CI)
Fixed effects 6 1118 0.51 (0.39 to 0.67)
Random effects 6 1118 0.51 (0.39 to 0.67)
Analyses excluding
    Netland et al31 5 523 0.54 (0.36 to 0.80)
    Parrish et al32 5 844 0.46 (0.33 to 0.64)
    Parmaksiz et al33 5 1084 0.53 (0.40 to 0.69)
    Chen et al34 5 1045 0.51 (0.39 to 0.67)
    Garcia-Feijoo et al35 5 1056 0.51 (0.39 to 0.68)
    Konstas et al36 5 1038 0.53 (0.40 to 0.71)

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