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Br J Ophthalmol 2009;93:864-865 doi:10.1136/bjo.2008.155291
  • Innovations

Treatment of inflamed pterygia or residual pterygial bed

  1. A M Mansour1,2
  1. 1
    Department of Ophthalmology, American University of Beirut, Beirut, Lebanon
  2. 2
    Rafic Hariri University Hospital, Beirut, Lebanon
  1. Professor A M Mansour, Department of Ophthalmology, American University of Beirut, PO Box 113-6044, Beirut, Lebanon; dr.ahmad{at}cyberia.net.lb
  • Accepted 22 February 2009

Abstract

Aims: To describe the use of subconjunctival bevacizumab or ranibizumab, an approved antivascular endothelial growth factor for wet macular degeneration, in halting the inflammation of a pterygium or a partially excised pterygium.

Methods: Case reports.

Results: Prompt regression of conjunctival microvessels in the pterygial bed was documented 1 week after a single subconjunctival injection of ranibizumab (one case) or bevacizumab (two cases). No side-effects were noted over 13 months of follow-up in the first case, 6 months in the second case and 1 month in the third case.

Conclusion: Selective blockade of vascular endothelial growth factor was effective in causing regression of conjunctival microvessels in three eyes with inflamed pterygium or residual pterygia.

Footnotes

  • Competing interests: None.

  • Ethics approval: Ethics approval was provided by Rafic Hariri University Hospital, Affiliate American University of Beirut.

  • Patient consent: Obtained.

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