rss
Br J Ophthalmol 2010;94:115-120 doi:10.1136/bjo.2009.162206
  • Original Article
  • Clinical science

Peripapillary retinal nerve fibre layer thickness profile in subjects with myopia measured using the Stratus optical coherence tomography

  1. M J Kim1,2,
  2. E J Lee1,3,
  3. T-W Kim1,3
  1. 1
    Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea
  2. 2
    Kong Eye Clinic, Seoul, Korea
  3. 3
    Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea
  1. Correspondence to Dr T-W Kim, Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 300 Gumi-dong, Bundang-gu, Seongnam, Gyeonggi-do 463-707, Korea; twkim7{at}snu.ac.kr
  • Accepted 22 July 2009
  • Published Online First 18 August 2009

Abstract

Background/aims: To evaluate the relationship between the axial length and refractive error and peripapillary retinal nerve fibre layer (RNFL) thickness profiles measured using Stratus optical coherence tomography (OCT) in subjects with myopia.

Methods: Forty-eight eyes of 48 myopic subjects were recruited and divided into three groups according to their spherical equivalent (SE): low myopia (−3.0 D<SE<0.0 D), moderate myopia (−6.0 D<SE≤−3.0 D) and high myopia (SE≤−6.0 D) groups. All individuals underwent the imaging with the Stratus OCT. The RNFL thickness profiles were compared between the groups.

Results: The global average RNFL was significantly thinner in the high myopia group than in the low myopia group (107.4 (SD 7.6) vs 115.8 (8.5) μm, p = 0.029 by post hoc test). For quadrant measures, the RNFL was thicker in the low myopia group than in the moderate and/or high myopia groups for the superior, nasal and inferior quadrants (all p values≤0.020). However, the temporal quadrant was thinner in the low myopia group than in the moderate and high myopia groups (p = 0.001).

Conclusion: High myopes had thinner RNFLs than did low myopes and showed different topographic profiles. Although the high myopes had significantly thinner RNFLs in the non-temporal sectors compared with the low myopes, they showed a significantly thicker RNFL in the temporal quadrant.

Footnotes

  • MJK and EJL contributed equally.

  • Funding Supported by a grant from the Seoul National University Bundang Hospital Research Fund.

  • Competing interests None.

  • Ethics approval Ethics approval was provided by the Institutional Review Board of the Seoul National University Bundang Hospital.

  • Patient consent Obtained.

  • Provenance and Peer review Not commissioned; externally peer reviewed.

This Article

  1. Abstract
  2. Full text
  3. PDF
  4. All Versions of this Article:
    1. bjo.2009.162206v1
    2. 94/1/115 most recent

Services

  1. Email this link to a friend
  2. Alert me when this article is cited
  3. Alert me if a correction is posted
  4. Alert me when eletters are published
  5. Article Usage Statistics
  6. Similar articles in this journal
  7. Similar articles in Web of Science
  8. Similar articles in PubMed
  9. Add article to my folders
  10. Download to citation manager
  11. Request permissions

Responses

  1. Submit a response
  2. No responses published

Social bookmarking

Register for free content


Free sample
 This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of BJO.
View free sample issue >>

Free archive
The full back archive is now available for BJO. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006, back to volume 1 issue 1.
Register to access the free archive >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.