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Anti-retinal autoantibodies-positive autoimmune retinopathy in cytomegalovirus-positive anterior uveitis
  1. Chui Ming Gemmy Cheung,
  2. Soon-Phaik Chee
  1. Singapore National Eye Centre, Singapore, Singapore
  1. Correspondence to Professor Chee Soon Phaik, Consultant, Medical Retina Service, Singapore National Eye Centre, 11 Third Hospital Avenue. Singapore 168751, Singapore; chee.soon.phaik{at}

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We report our experience with the long-term management (13 years) of a patient with unilateral Posner–Schlossman syndrome (PSS), in whom cytomegalovirus (CMV) DNA was detected. Multiple treatment modalities were employed to control the number of relapses. Extensive retinal damage was observed even though clinically apparent retinitis was never observed during the follow-up period.


A 48-year-old man had suffered from recurrent right hypertensive anterior uveitis since 1996 and was diagnosed with PSS on clinical grounds. The condition was controlled with intermittent topical corticosteroid and anti-glaucoma medications. A superior defect was documented in 2003 (figure 1) despite healthy optic discs with cup-to-disc ratio of 0.4 bilaterally. This was felt to result from intermittent high pressure spikes, despite intraocular pressure returning to normal between attacks.

Figure 1

Humphrey's visual field from 2003, 2005, 2006 and 2009 showing progressive constrictive …

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