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Prevalence of heterophoria and associations with refractive error, heterotropia and ethnicity in Australian school children
  1. Jody F Leone1,
  2. Elaine Cornell1,
  3. Ian G Morgan2,
  4. Paul Mitchell3,
  5. Annette Kifley3,
  6. Jie Jin Wang3,
  7. Kathryn A Rose1
  1. 1Discipline of Orthoptics, Faculty of Health Sciences, University of Sydney, Sydney, Australia
  2. 2ARC Centre of Excellence in Vision Science, School of Biology, The Australian National University, Canberra, Australia
  3. 3Department of Ophthalmology (Centre for Vision Research, Westmead Millennium Institute, Westmead Hospital), University of Sydney, Westmead, Australia
  1. Correspondence to Dr Kathryn A Rose, Discipline of Orthoptics, Faculty of Health Sciences, University of Sydney (Cumberland Campus), PO Box 170, Lidcombe NSW 1825, Australia; k.rose{at}usyd.edu.au

Abstract

Aims To establish the prevalence of heterophoria and its association with refractive error and ethnicity in a population-based study of Australian schoolchildren.

Methods The Sydney Myopia Study is a stratified, random cluster (school-based) sample of 4093 students (examined: 2003–2005). Two samples aged 6 (n=1692) and 12 years (n=2289) without heterotropia were included. Prevalent heterophoria was assessed using cover un-cover and prism bar alternate cover testing at 33 cm and 6 m distance fixation. Cycloplegic autorefraction (1% cyclopentolate) was performed. Significant refractive error was defined as ≤−0.50SE and ≥+2.00SE.

Results Exophoria was highly prevalent at near fixation (age 6: 58.3%, age 12: 52.2%). Orthophoria predominated at distance fixation (age 6: 85.4%, age 12: 90.9%). Hyperopia was associated with esophoria at near (age 6: OR 1.7, 95% CI 1.1 to 2.8, age 12: OR 2.9, CI 1.1 to 2.8) and distance fixation (age 6: OR 9.7, CI 3.5 to 26, age 12: 9.6 OR, CI 4.2 to 22). Myopia was associated with exophoria at near (OR 2.1, CI 1.5 to 2.7) and distance fixation (OR 3.1, CI 2.1 to 4.4) for 12-year-old children only. Exophoria was more frequent in children of East Asian than European Caucasian origins, even after adjusting for refraction; at near (age 6: OR 1.4, CI 1.0 to 2.0, age 12: OR 1.4, CI 1.0 to 1.9) and distance (age 12: OR 1.7, CI 1.1 to 2.7).

Conclusion Contrary to other studies, exophoria, not orthophoria, was predominant for near. Exophoria was more prevalent in children of East Asian origin. Longitudinal studies are needed to establish if incident heterotropia is preceded by heterophoria.

  • Strabismus/phoria
  • exotropia/exophoria/esotropia/esophoria
  • refractive errors
  • ethnic groups
  • epidemiology
  • muscles
  • optics and refraction
  • public health
  • child health (paediatrics)

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Footnotes

  • Funding Funding for the Sydney Myopia Study was provided by a grant from the Australian National Health & Medical Research Council (ID 253732) and the Vision Co-operative Research Centre. IGM's contribution was supported by a grant from the Australian Research Council (COE561903). JFL holds a National Health and Medical Research Council Biomedical (Dora Lush) Postgraduate Research Scholarship (Scholarship ID 457173).

  • Competing interests None.

  • Patient consent Obtained.

  • Ethics approval Ethics approval was provided by the University of Sydney Human Research Ethics Committee and Department of Education and Training NSW.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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