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Change in optic nerve head topography in healthy volunteers: an 11-year follow-up
  1. Mika Harju1,
  2. Leena Kurvinen1,
  3. Jukka Saari1,
  4. Eija Vesti1,2
  1. 1Helsinki University Eye Hospital, Helsinki, Finland
  2. 2Turku University Hospital, Turku, Finland
  1. Correspondence to Dr Mika Harju, Helsinki University Eye Hospital, Haartmaninkatu 4 C, PO Box 220, 00029 HUS, Helsinki, Finland; mika.harju{at}hus.fi

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Introduction

Detection of progressive optic nerve head (ONH) changes in follow-up of glaucoma is fundamental. We know from histological studies, however, that non-glaucomatous eyes also undergo a decline in the number of nerve fibres in the ONH with age.1 2 Up-to-date technologies for ONH imaging provide a high resolution and high reproducibility,3–5 and may be more sensitive than are clinicians in detecting ONH changes.6 7 The question arises whether the normal age-dependent decline in the number of optic nerve fibres causes any detectable changes in ONH topography as measured with scanning laser ophthalmoscopy (SLO); this has been suggested in some cross-sectional studies8 9 whereas others have …

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