Article Text
Clinical science
Original article
Cerebrospinal fluid dynamics between the basal cisterns and the subarachnoid space of the optic nerve in patients with papilloedema
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- Cerebrospinal fluid
- cisternography
- intracranial pressure
- papilloedema
- pseudotumor cerebri
- optic nerve
- imaging
Introduction
Patients with increased intracranial pressure (ICP) often develop papilloedema. This potentially vision-threatening ophthalmological condition results from transmission of the increased ICP to the subarachnoid space (SAS) of the optic nerve (ON). The associated increase in cerebrospinal fluid (CSF) volume in the perioptic space results in unfolding of the ON sheath, and it is believed that this, in turn, compresses the nerve, causing stasis of axonal transport, thus producing swelling of the ON axons.1–5 Pressure measurements in the SAS surrounding the ON have not been performed in this setting, but it has been assumed that the pressure in the SAS is the same as that measured during lumbar …