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Br J Ophthalmol 96:137-138 doi:10.1136/bjophthalmol-2011-300441
  • PostScript
  • Letter

Gender differences in re-epithelialisation time in fungal corneal ulcers

  1. Nisha R Acharya4
  1. 1Aravind Eye Care System, Pondicherry, India
  2. 2Aravind Eye Care System, Madurai, India
  3. 3Vision Science School, School of Optometry, University of California, Berkeley, California, USA
  4. 4FI Proctor Foundation, University of California San Francisco (UCSF), San Francisco, California, USA
  1. Correspondence to Dr Nisha R Acharya, FI Proctor Foundation, Room S309, 513 Parnassus Avenue, UCSF, San Francisco, CA 94143-0412, USA; nisha.acharya{at}ucsf.edu

  1. Contributors TK: PI of Pondicherry centre, involved in design of study, reviewed and interpreted results, drafting and critical review of manuscript; NVP: PI of Madurai site, design of study, interpretation of result, critically reviewed manuscript; KG: study concept and design, analysis of data, drafting manuscript; CEO: data collection, analysis, drafted and revised manuscript; KJR: data collection, analysis, critical review of manuscript; JDK: investigator, analysis and interpretation of data, critical revision of manuscript; TML: co-PI of study, study design, implementation of study, obtaining funding, interpretation of results, critical review of manuscript; NRA: co-PI of study, design of study, review and interpretation results, drafting and revision of manuscript, and responsibility for integrity of study and results.

  • Accepted 27 August 2011
  • Published Online First 6 October 2011

Introduction

Animal studies have demonstrated that female mice may have a slower re-epithelialisation following corneal injury compared with males.1 However, it is unknown if this translates to humans. In this report, we compare re-epithelialisation time in men and women using data collected as part of a prospective, randomised clinical trial on fungal corneal ulcers.

Methods

Clinical outcome measures were obtained in a standardised manner from a clinical trial on fungal corneal ulcers, which has been previously described.2 Patients were …

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