Menu

rss
Br J Ophthalmol 96:62-67 doi:10.1136/bjo.2010.193581
  • Clinical science

Impairment of contrast visual acuity as a functional correlate of retinal nerve fibre layer thinning and total macular volume reduction in multiple sclerosis

Table 2

Overview of contrast box and optical coherence tomography measurements

Control Multiple sclerosis Generalised Estimating Equation
Mean SD Min Max Mean SD Min Max CI low CI high p Value
Area under the curve Day 2.087 0.111 1.857 2.319 1.908 0.215 1.067 2.236 −0.215 −0.115 <0.001
Area under the curve Night 1.792 0.202 1.108 2.173 1.586 0.305 0.650 2.185 −0.263 −0.100 <0.001
Mean retinal nerve fibre layer thickness (μm) 104.1 9.0 83 126 96.4 13.5 46 133 −11.7 −3.6 <0.001
Total macula volume (mm3) 7.071 0.375 6.293 8.050 6.838 0.471 5.455 7.674 −0.357 −0.034 0.018

  • Differences between multiple sclerosis and healthy control eyes were analysed using Generalised Estimation Equations accounting for intersubject relations and correcting for age.

This Article

  1. Abstract
  2. Full text
  3. PDF

Register for free content


Free sample
This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of BJO.
View free sample issue >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.