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Natamycin and voriconazole in Fusarium and Aspergillus keratitis: subgroup analysis of a randomised controlled trial

https://doi.org/10.1136/bjophthalmol-2012-301825

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    Footnotes

    • Contributors NVP designed study, collected data, drafted and approved the manuscript; PL designed the study, collected data, and critically revised and approved the manuscript; JM collected data and critically reviewed and approved the manuscript; TK designed the study, collected data, and critically reviewed and approved the manuscript; MS collected data and critically reviewed and approved the manuscript; CMV collected data and critically reviewed and approved the manuscript; CEO collected data, conducted analyses, drafted, reviewed, and approved the manuscript; AS conducted analyses, drafted, reviewed, and approved the manuscript; JDK designed study, assisted with analyses, critically reviewed and approved the manuscript; TCP designed study, conducted analyses, and critically reviewed and approved the manuscript; NRA designed study, collected data, obtained funding, and critically reviewed and approved the manuscript; TML designed study, obtained funding, oversaw entire study, and drafted, reviewed, and approved the manuscript.

    • Funding Alcon Inc donated natamycin, and Pfizer Inc donated voriconazole for the study. None of the authors have any financial disclosures related to this manuscript. Funding for this research was from That Man May See and the South Asia Research Fund. The Department of Ophthalmology at UCSF is supported by a core grant from the National Eye Institute, EY02162. Dr Acharya is supported by a National Eye Institute K23EY017897 grant and a Research to Prevent Blindness Career Development Award. Dr Lietman is supported by a National Eye Institute grant U10-EY015114 and a Research to Prevent Blindness award. Dr Porco is supported by That Man May See Foundation at UCSF. The sponsors did not have role in the design and conduct of the study; collection, management, analysis and interpretation of the data; and preparation, review or approval of the manuscript.

    • Competing interests None.

    • Ethics approval University of California, San Francisco Committee on Human Research; Aravind Eye Hospital Institutional Review Board.

    • Provenance and peer review Not commissioned; internally peer reviewed.