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Ageing and physiological changes in rod-mediated dark adaptation
  1. Seshubabu Gosala
  1. Correspondence to Dr Seshubabu Gosala, Department of Ophthalmology, Visakha Eye Hospital, Visakhapatnam 530 017, Andhra Pradesh, India; seshu.gosala{at}

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Clark et al have mentioned ‘cross-sectional design’ and ‘fixation instability in participants with seriously impaired acuity’ as the limitations of the study in their article published in the latest issue of the British Journal of Ophthalmology.1

However, one important limitation is that they have not compared the results of ‘spectral domain optical coherence tomography and dark adaptation correlation’ with normal age-matched controls without age-related maculopathy (ARM) and in patients with advanced ARM. The comparison of the dark adaptation in age-matched normal subjects …

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