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Brimonidine is a well-recognised cause of ocular surface disease but is less widely known to cause uveitis. We present important clinical lessons from five new cases of brimonidine-associated anterior uveitis.
1. A 64-year-old man with primary open-angle glaucoma presented with red eyes and visual halos. He had used brimonidine 0.2%, timolol 0.5% and bimatoprost 0.03% for 13 months. There was bilateral anterior chamber inflammation with diffuse pigmented and stellate keratic precipitates. His intraocular pressure was 21 mm Hg bilaterally, rising to 26 mm Hg 3 weeks later. A trabeculectomy was planned, but cessation of brimonidine …