Review of endophthalmitis following Boston keratoprosthesis type 1
- Department of Ophthalmology, Centre Hospitalier de l'Université de Montréal (CHUM), Hôpital Notre-Dame, Montréal, Québec, Canada
- Correspondence to Dr Mona Harissi-Dagher, Department of Ophthalmology, Notre-Dame Hospital, 1560, rue Sherbrooke Est, Montréal, Québec H2L 4M1, Canada;
Contributors M-CR and KM performed the literature review, analysed the data and wrote the manuscript. MH-D was responsible for the article's conception and design. M-CR and MH-D also revised the article critically for important intellectual content.
- Accepted 3 March 2012
- Published Online First 4 April 2012
Endophthalmitis remains one of the most damaging and challenging complications following Boston keratoprosthesis type 1 (KPro) surgery. The authors reviewed the literature from 2001 onward to identify cases of endophthalmitis following KPro surgery and present an additional case of endophthalmitis in a patient with Stevens Johnson syndrome. The prevalence of endophthalmitis between 2001 and 2011 was 5.4%. Gram-positive bacteria are the most common agents responsible for endophthalmitis in this patient population while gram-negative bacteria and fungi are emerging pathogens. Risk factors for endophthalmitis include preoperative diagnosis of cicatricial disease and postoperative infectious keratitis, glaucoma drainage device erosion and non-compliance with antibiotic prophylaxis. Additional studies on the prevention and treatment of endophthalmitis are required to improve the overall prognosis of these patients.
Competing interests None.
Patient consent Obtained.
Ethics approval The study consists of the case reports . Ethics committee/IRB approval is not required for case reports.
Provenance and peer review Not commissioned; externally peer reviewed.
Data sharing statement The authors will share the original study protocol and the dataset used for the analysis upon request.