Article Text

PDF
Position of the central retinal vessel trunk and pattern of remaining visual field in advanced glaucoma
  1. Haili Huang1,
  2. Jost B Jonas2,
  3. Yi Dai1,
  4. Jiaxu Hong1,
  5. Min Wang1,
  6. Junyi Chen1,
  7. Jihong Wu1,
  8. Xinghuai Sun1,3
  1. 1Department of Ophthalmology and Vision Science, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, China
  2. 2Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University, Heidelberg, Germany
  3. 3State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Fudan University, Shanghai, China
  1. Correspondence to Prof. Xinghuai Sun, M.D., Ph.D., Department of Ophthalmology, Shanghai Eye, Ear, Nose and Throat Hospital, School of Shanghai Medicine, Fudan University, 83 Fenyang Road, Shanghai 200031, China;xhsun{at}shmu.edu.cn

Abstract

Background To investigate the association between the position of the central retinal vessel trunk (CRVT) in the optic nerve head and the pattern of remaining visual field and thickness of the retinal nerve fibre layer (RNFL) in end-stage glaucoma.

Methods The clinical observational study included patients with end-stage glaucoma with a remaining central visual field island (CI-group) or temporal visual field remnant (TI-group). The position of the CRVT exit on the lamina cribrosa was evaluated on optic disc photographs. The RNFL thickness was measured by optical coherence tomography.

Results The study included 21 glaucoma patients with a remaining central visual field island and 22 glaucoma patients with a temporal visual field remnant. Both groups did not differ significantly in age, gender, refractive error, central corneal thickness, axial length and mean RNFL thickness. RNFL in the temporal region (48.1±5.5 μm vs 37.2±7.9 μm; p<0.001) was significantly thicker, and RNFL in the nasal region (41.6±8.3 μm vs 48.0±7.8 μm; p=0.01) was significantly thinner in the CI-group than TI-group. The CRVT was located in the temporal disc part significantly more often in the CI-group than in the TI-group (6/21 vs 0/22; p=0.009). The distance from the CRVT to the temporal disc border expressed as percentage of total disc diameter was significantly smaller in the CI-group than in the TI-group(0.55±0.07 vs 0.79±0.08; p<0.001).

Conclusions The pattern of perimetric loss was associated with the CRVT position: eyes with a central visual field island tended to have the CRVT in the temporal optic disc region.

  • Glaucoma
  • Optic Nerve

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.