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Prevalence of ocular abnormalities in adults with Down syndrome in Hong Kong
  1. Angie Hon Chi Fong1,
  2. Jennifer Shum2,
  3. Alex L K Ng2,
  4. Kenneth K W Li2,4,
  5. Sarah McGhee3,
  6. David Wong1,4
  1. 1Department of Ophthalmology, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China
  2. 2Department of Ophthalmology, United Christian Hospital, Kowloon, Hong Kong SAR, China
  3. 3Department of Community Medicine, The University of Hong Kong, Hong Kong SAR, China
  4. 4Department of Ophthalmology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
  1. Correspondence to Dr Angie Hon Chi Fong, Hong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong Kong SAR, China; ahcfong{at}gmail.com

Abstract

Background/aims This was a cross-sectional survey to find the prevalence of visual impairment and eye diseases among adults with Down syndrome (DS) in Hong Kong.

Methods 91 DS patients over the age of 30 were recruited through the Hong Kong Down Syndrome Association. Each patient was provided with a complete ophthalmological assessment including best corrected visual acuity, refraction, slit lamp and fundus examination.

Results In our sample, 56.6% had normal vision to mild vision impairment, 33.7% and 7.2% had moderate and severe vision impairment, respectively, and 2.4% were blind. The mean presenting distant LogMAR visual acuity was 0.66 (Snellen equivalent 20/90), and the best corrected LogMAR visual acuity was 0.48 (Snellen equivalent 20/60). Significant refractive errors were found in 86.3% of the eyes, with spherical equivalent corrections ranging from −23.25D to +3.00D. Myopia and astigmatism were prevalent and found in 59.3% and 72.7% of the eyes, respectively. Blepharitis and chalazion were found in 44% of the eyes, while corneal problems were present in 27.5%. There were low incidences of infective keratitis (0.5%), keratoconus (0.5%) and Brushfield spots (1.1%). Cataracts were found in 72.2% of the eyes; 26.1% were congenital and 44.9% were age-related. Fundal abnormalities were present in 49.5% of the eyes.

Conclusions There is a high prevalence of vision impairment among Chinese DS adults. Uncorrected refractive errors, high myopia and cataracts are the main visually debilitating ophthalmological abnormalities. Vision may be improved through the simple use of glasses and early treatment of age-related cataracts.

  • Epidemiology
  • Vision
  • Public Health
  • Eye (Globe)

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