Article Text

PDF
Trends in bacterial and fungal keratitis in South India, 2002–2012
  1. Prajna Lalitha1,
  2. Namperumalsamy V Prajna2,
  3. Geetha Manoharan1,
  4. Muthiah Srinivasan2,
  5. Jeena Mascarenhas2,
  6. Manoranjan Das2,
  7. Sean S D'Silva2,
  8. Travis C Porco3,4,5,
  9. Jeremy D Keenan3,4
  1. 1Department of Ocular Microbiology, Aravind Eye Care System, Madurai, India
  2. 2Department of Cornea and External Diseases, Aravind Eye Care System, Madurai, India
  3. 3Francis I. Proctor Foundation, University of California, San Francisco, USA
  4. 4Department of Ophthalmology, University of California, San Francisco, USA
  5. 5Department of Epidemiology & Biostatistics, University of California, San Francisco, USA
  1. Correspondence to Dr Prajna Lalitha, Department of Ocular Microbiology, Aravind Eye Care System, 1 Anna Nagar, Madurai, Tamil Nadu 625 020, India; lalitha{at}aravind.org

Abstract

Objective To assess the trends in microbiological organisms identified from corneal scrapings from patients with infectious keratitis at a tertiary care medical centre in South India.

Methods We reviewed the records of the microbiology laboratory at Aravind Eye Hospital in Madurai, India, from 2002 until 2012. We identified the microbiological causes of all corneal ulcers from the culture and smear results, and assessed for trends in bacterial and fungal keratitis over time.

Results Of 23 897 corneal patients with ulcer with a corneal smear from 2002 to 2012 a fungal organism was identified in 34.3%, a bacterial organism in 24.7% and no organism in 38.3%. During this period, the annual number of keratitis cases due to bacteria decreased from 677 to 412, and the annual number due to fungus increased from 609 to 863. In analyses accounting for the total number of outpatients seen each year, the decline in number of smears positive for bacteria was statistically significant (p<0.001) but the increase in the number positive for fungus was not (p=0.73). The relative frequency of individual bacterial or fungal organisms remained relatively stable over this time.

Conclusions At a tertiary eye care centre in South India, there has been a reduction in the numbers of smear-positive bacterial keratitis over the past 11 years. This decline likely reflects economic development in India and increased access to antibiotics.

  • Cornea
  • Microbiology

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • At a glance
    Keith Barton James Chodosh Jost Jonas