Aims: To assess the utility of OCT in a nurse led, fast track clinic for new AMD referrals and to see how often ICG led to an additional diagnosis to that provided by FFA.
Method: Retrospective audit of a consecutive series of 134 new patients referred with suspected wet AMD. When visual acuity was ≥6/60 an OCT was performed. If the OCT was consistent with 'wet' AMD the patient underwent simultaneous FFA/ICG. The sensitivity and specificity of this clinic was calculated. The number of additional diagnoses made using ICG was recorded.
Results: 23/134 (17.16%) patients had OCT only and were not subsequently found to have 'wet' AMD. FFA/ICG was performed in 111 patients, which showed 'wet' AMD in 90/111 (81%). OCT as used in our clinic had a sensitivity of 1 and specificity of 0.65 for detecting wet AMD. ICG provided additional diagnoses in 19 (14.17%) patients. ICG detected a specific vascular abnormality in 58% of the occult cases.
Conclusions: OCT proved to be an effective screening tool for wet AMD in this clinic with excellent sensitivity and reasonable specificity. ICGA provided an additional diagnosis in a significant number of cases, but did not define a vascular abnormality in all occult cases.
- indocyanine green angiography
- optical coherence tomography
- wet age related macular degeneration
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