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Glaucoma Detection with Matrix and Standard Achromatic Perimetry
  1. Zvia Burgansky-Eliash (zviaeb{at}gmail.com),
  2. Gadi Wollstein (wollsteing{at}upmc.edu),
  3. Avni Patel (patel.avni{at}gmail.com),
  4. Richard A Bilonick (bilonickra{at}upmc.edu),
  5. Hiroshi Ishikawa (ishikawah{at}upmc.edu),
  6. Larry Kagemann (kagemannl{at}upmc.edu),
  7. William D Dilworth (dilworthb{at}upmc.edu),
  8. Joel S Schuman (schumanjs{at}upmc.edu)
  1. UPMC Eye Center, Eye & Ear Inst, Ophthalmol and Vis Sci Res Cent, U Pitt Sch of Med, United States
  2. UPMC Eye Center, Eye & Ear Inst, Ophthalmol and Vis Sci Res Cent, U Pitt Sch of Med, United States
  3. UPMC Eye Center, Eye & Ear Inst, Ophthalmol and Vis Sci Res Cent, U Pitt Sch of Med, United States
  4. UPMC Eye Center, Eye & Ear Inst, Ophthalmol and Vis Sci Res Cent, U Pitt Sch of Med, United States
  5. UPMC Eye Center, Eye & Ear Inst, Ophthalmol and Vis Sci Res Cent, U Pitt Sch of Med, United States
  6. UPMC Eye Center, Eye & Ear Inst, Ophthalmol and Vis Sci Res Cent, U Pitt Sch of Med, United States
  7. UPMC Eye Center, Eye & Ear Inst, Ophthalmol and Vis Sci Res Cent, U Pitt Sch of Med, United States
  8. UPMC Eye Center, Eye & Ear Inst, Ophthalmol and Vis Sci Res Cent, U Pitt Sch of Med, United States

    Abstract

    Purpose: Matrix perimetry is a new iteration of frequency doubling technology (FDT) using a smaller target size in the standard achromatic perimetry presentation pattern. This study compared Matrix and Swedish interactive thresholding algorithm (SITA) perimetry performance in detecting glaucoma diagnosed by structural assessment.

    Design: Prospective cross-sectional study.

    Methods: Seventy-six eyes of 76 consecutive healthy subjects, glaucoma suspects and glaucoma patients were included. All patients underwent optic nerve head (ONH) photography, SITA and Matrix perimetry and optical coherence tomography (OCT; Stratus OCT) within a six month interval. Glaucoma diagnosis was established by either glaucomatous optic neuropathy or OCT retinal nerve fiber layer (RNFL) thickness. Mean deviation (MD), pattern standard deviation (PSD), glaucoma hemifield test (GHT) and cluster of abnormal testing locations were recorded from Matrix and SITA.

    Results: Similar correlations were observed with Matrix and SITA MD and PSD with either cup-to-disc ratio or OCT mean RNFL. The area under the receiver operating characteristic (AROC) curves of MD and PSD for discriminating between healthy and glaucomatous eyes ranged from 0.69 to 0.81 for Matrix and from 0.75 to 0.77 for SITA. There were no statistically significant differences among any corresponding Matrix and SITA AROCs.

    Conclusions: Matrix and SITA perimetry had similar capabilities for distinguishing between healthy and glaucomatous eyes regardless of whether the diagnosis was established by ONH or OCT RNFL assessment.

    • Glaucoma
    • Visual field

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