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Comparison of anterior chamber depth measurements using the IOLMaster, Scanning Peripheral Anterior Chamber depth Analyser and Anterior Segment Optical Coherence Tomography
  1. Raghavan Lavanya,
  2. Livia Teo,
  3. David S Friedman,
  4. Han T Aung,
  5. Mani Baskaran,
  6. Hong Gao,
  7. Tamuno Alfred,
  8. Steve K Seah,
  9. Kenji Kashiwagi,
  10. Paul J Foster,
  11. Tin Aung (tin11{at}pacific.net.sg)
  1. Singapore National Eye Centre, Singapore
  2. Singapore National Eye Centre, Singapore
  3. Wilmer Eye Institute and Johns Hopkins Bloomberg School of Public Health,, United States
  4. Singapore Eye Research Institute, Singapore, Singapore
  5. Singapore Eye Research Institute, Singapore, Singapore
  6. Clinical Trials and Epidemiological Research Unit, Singapore, Singapore
  7. Clinical Trials and Epidemiological Research Unit, Singapore, Singapore
  8. Singapore National Eye Centre, Singapore
  9. University of Yamanashi, Chuo Yamanashi, Japan, Japan
  10. Institute of Ophthalmology and Moorfields Eye Hospital, London,U.K., United Kingdom
  11. Singapore National Eye Centre, Singapore

    Abstract

    Aim: To compare anterior chamber depth (ACD) measurement by three non-contact devices, the IOLMaster, Scanning Peripheral Anterior Chamber Depth Analyser (SPAC) and Visante Anterior Segment Optical Coherence Tomography (AS-OCT)

    Methods: This was a prospective, cross-sectional study of 497 phakic subjects above the age of 50 attending a community clinic in Singapore. ACD of right eyes in subjects was measured using IOLMaster, SPAC and AS-OCT by the same investigator. The ACD was measured from the corneal epithelium to the anterior lens surface, and ACD measurements were compared using Bland- Altman analysis.

    Results: A total of 232 men and 265 women were examined, with a mean age of 63.4 ± 7.9 (SD) years. The mean ACD was 3.08 ± 0.36 mm with IOLMaster, 3.10 ± 0.44 with SPAC and 3.14 ± 0.34 with AS-OCT. A significant difference was noted between the ACD measurements recorded by the three devices (p <0.0001) with AS-OCT measurements being deeper than IOLMaster and SPAC. The mean difference between AS-OCT and IOLMaster measurements was 0.062 ± 0.007 mm (p<0.0001, 95% limits of agreement (LoA): -0.37mm to 0.25mm); between AS-OCT and SPAC was 0.035 ± 0.011 (p=0.0001, 95% LoA: -0.44mm to 0.51mm) and between SPAC and IOLMaster was 0.027 ±0.012 (p=0.027, 95% LoA: -0.57mm to 0.50mm).

    Conclusions: AS-OCT measurements of ACD are deeper than those with SPAC and IOLMaster. However, as the differences found were small, they are unlikely to be clinically important.

    • angle closure
    • anterior chamber depth
    • anterior segment
    • anterior segment OCT
    • biometry

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