Aims To determine the effect of contact lens-induced oedema on the accuracy of Goldmann tonometry measurements of intraocular pressure (IOP) in mature subjects.
Methods: 22 healthy subjects aged between 50 and 60y were recruited for this study. Corneal curvature, IOP, and central corneal thickness (CCT) were measured before and after 2h of monocular closed-eye wear of a thick hydroxyethyl methacrylate (HEMA) contact lens. Measurements were then repeated at 20min intervals for 1h after lens removal.
Results: CCT (+54.1μm) and IOP (+2.7mmHg, p<0.001, paired t-test with Bonferroni correction) increased significantly after lens wear. For the hour following lens removal, the measured IOP was correlated to the increase in CCT (r=0.84, p<0.001), at a rate of 1.0mmHg/10μm (95% CI 0.8-1.2mmHg/10μm, linear mixed model analysis).
Conclusion: A relatively small increase in CCT due to contact lens-induced corneal oedema caused an overestimation error in Goldmann tonometry measurements of IOP in healthy mature subjects.
- corneal thickness
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